EFSA evaluates risk of MRSA in food and animals

In the case of food-producing animals, a specific type of MRSA, called CC398, has emerged and is most often carried without symptoms by intensively reared animals. The Panel noted that this strain A subtype of a microbe defined by its genetic make-up; for example, in the case of Escherichia coli O157, the 'O157' part of the name refers to the strain. represents a small proportion of the overall cases of MRSA in the European Union. Various types of MRSA, including CC398, can be found in slaughterhouses and on raw meat, but the Panel stated that, based on current data, the risk of infection for slaughterhouse workers and persons handling meat appears to be low.

Professor Dan Collins, chair of the BIOHAZ Panel, said: “There’s no evidence to date that humans can become infected with the CC398 strain of MRSA from eating contaminated food. Neither is there evidence that this strain has caused food poisoning.”

The Panel further noted that the occurrence The fact or frequency of something (e.g. a disease or deficiency in a population) happening. of CC398 varies widely throughout Europe. A risk for people in contact with live food-producing animals has been identified and veterinarians and farmers, as well as their families, are at greater risk of becoming carriers or infected than the general population. In affected countries, the CC398 strain is mostly detected in pigs, veal calves, and broiler chickens.

Animal pets can also become infected with MRSA, but almost in all cases the bacteria is passed from humans to pets and then back to humans. The Panel noted that there are no specific studies available which examined the relative risk of different small animals and horses as sources of infection in humans.

Regarding control options, the Panel said that animal movement and contact between animals are each likely to be an important factor for the transmission of CC398. The Panel said that since the most important routes of transmission to humans are through direct contact with live animals and their environments, the most effective control measures are likely to be at farm level.

The BIOHAZ Panel also said that systematic monitoring of MRSA should be carried out to evaluate trends in the development of MRSA in food-producing animals in all Member States. Further work should be performed on harmonising methods for sampling, detecting and quantifying MRSA in humans and animals, and for detecting MRSA as a contaminant Any substance occurring in foodstuffs that was not added intentionally. Contaminants can arise from packaging, food processing and transportation, farming practices or the use of animal medicines. The term does not include contamination from insects or rodents. in food, and in the environment. The Panel also recommended that guidelines for screening of patients admitted to hospitals should be expanded to include professional categories exposed to intensively reared livestock.

The Scientific Opinion of EFSA’s BIOHAZ Panel, to which the European Centre for Disease Control and Prevention (ECDC) also contributed, was carried out in parallel with the work of the European Medicines Agency (EMEA) on other aspects of MRSA. EMEA has published a reflection paper on the use of antimicrobials in livestock and companion animals in relation to the risk of MRSA infection in animals. (EMEA reflection paper). A summary paper bringing together the findings on the topic of MRSA by the three EU agencies is scheduled to be published later in the year.

• Assessment of the Public Health significance of meticillin resistant Staphylococcus aureus (MRSA) in animals and foods